PGC provides unique retention and separation of very polar compounds. Its surface is stereo-selective with the capability to separate geometric isomers, diastereomers and other closely related compounds. Hypercarb is stable throughout the entire pH range 0-14, and is not affected by aggressive mobile phases. Its compatibility with all solvent systems enables separation of a wide range of polarities within a single chromatographic run. The selectivity of the Hypercarb packing is different from the selectivity of silica and polymeric phases. Its retention mechanism is different from conventional C18 columns.

In order to assist you in using this unique chromatographic column we have produced the following two pieces of information:

• Hypercarb Method Development Guide



• Hypercarb Applications Notebook

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